A roadside bomb ripped through a van carrying civilians on a road used by foreign troops in eastern Afghanistan on Wednesday, killing 10 and wounding six, officials said.
In the south, three Australian soldiers were wounded in another blast.
The attacks are a reminder of the dangers facing Afghan and foreign forces as thousands of new U.S. troops roll into the country to try to reverse the Taliban gains of the last three years.
They also came a few days before President Barack Obama unveils his plan to tackle the deteriorating situation in Afghanistan and neighboring Pakistan, which is battling an Islamic insurgency of its own.
The explosion that killed the civilians happened in Sabari district of the eastern Khost province while the van was on a road also used by foreign and Afghan troops, said Police Chief Abdul Qajum Bakizoy. He blamed Taliban militants for planting the bomb.