The world's fourth best doubles duo of Daniela Hantuchova and Ai Sugiyama proved to be too strong for Shahar Pe'er and Marion Bartoli in Los Angeles on Monday.
The Israeli/French team lost 6-4, 6-3 to the number three seeds in the first round of the JPMorgan Chase Open.
Pe'er and Bartoli were outplayed by the Hantuchova and Sugiyama and will hope for a better result in their singles matches.
Pe'er was scheduled to play her first round match against Shuai Peng of China late on Tuesday and will face Paola Suarez of Argentina in the second round should she win.
The number one Israeli, who climbed to No. 25 in the latest WTA rankings, will be desperate to end her current singles rot which has seen her lose five of her last seven matches.
Israeli doubles duo Andy Ram and Yoni Erlich will be in action on Wednesday in the second round of the Rogers Cup in Toronto.
The pair, who are ranked sixth, received a first round bye and will play the winners of the first round match between Wayne Arthurs and Dominik Hrbaty and Argentineans Jose Acasuso and David Nalbandian.