Such big cats include lions and tigers that should not go through the process of onychectomy, researchers say.
Germany's federal office for civil protection issued a warning to locals, also advising them to keep any pets indoors.
The cub, newly named Zion-Neev, is adapting to his new life at the Simbonga Game Reserve & Sanctuary.
19-year-old Loonkito was killed after targeting local livestock.
Border Police detectives worked to find the cub after videos of it in various locations were posted on social media in the last few weeks.