A woman who is a HIV carrier has donated a kidney to her husband, who also is a
carrier of the AIDS virus, Tel Aviv Sourasky Medical Center reported on
The surgery, the first of its kind in the world between living
patients, took place a a few months ago, the hospital said, and the recipient
has returned to work and normal functioning.
The Tel Aviv transplant
required a long and careful preparation by the interdisciplinary transplant team
that included doctors from the hospital’s AIDS center and its transplant center,
as well as psychologists and social workers.
The procedure is complicated
by the need to change the drugs taken by the HIV carriers to raise the prospects
for success and prevent conflicts between drugs to minimize rejection of the
organ and medications for HIV.
“Organs from HIV carriers have never been
used for transplant before anywhere in the world, except in South Africa, where
it has been done successfully using organs from braindead patients for many
years,” said Dr. Roni Baruch, head of Sourasky’s transplant clinic. “On the
basis of the South African experience and the growing awareness that HIV is no
longer the fatal disease it used to be, there is recognition in the Western
world of the possibility that HIV carriers can undergo lifesaving organ
transplants. Of course, such organs will be given only to HIV carriers
The couple involved were a man who had been on dialysis for
two years and his wife – both of them HIV carriers. Following the surgery, whose
date was not given, both are under close observation to ensure that their kidney
function and immune systems are stable.
“The fact that this was the first
live-kidney transplantation between HIV carriers gives a new perspective for
medicine with HIV carriers, said Dr. Yvgeny Katzman, an infectious disease
expert at Sourasky’s AIDS center.
The doctors said that due to much
experience in South Africa with kidney and even liver donations from brain-dead
patients to HIV patients, the success rate of transplants has risen to be almost
equal to those of non-carriers. Liver and kidney infections are quite common
among HIV carriers, they added.
The participants in the surgery are
preparing an article about Israel’s first live kidney donation and transplant
between HIV carriers that will be published in a medical journal. The case will
also be presented at medical conferences in Israel and abroad.