In a new Internet posting published on Monday, Al-Qaida's deputy leader accuses US President Barack Obama of cheating the Arab world by failing to advance Middle East peace talks.
In the meddage, Ayman Al-Zawahri said the US president's Mideast policy is "another cycle in the Crusader and Zionist campaign to enslave and humiliate us."
Al-Zawahri also urged Muslims and Palestinians to wage holy war outside Israel and the Palestinian territories, and praised Muslim militants fighting in Pakistan.
While the 25-minute audio message focuses on Obama, Zawahri also scoffs at key American allies in the region, the Egyptian president and the Jordanian king, for making peace with Israel.
The authenticity of Monday's message could not be independently confirmed.