Israeli forces shot and killed a Palestinian-American youth during clashes on Friday, the US State Department said, calling for a quick and transparent investigation.
Orwah Hammad, 14, was shot in the head in the village of Silwad, north of the Palestinian seat of government in Ramallah.
An Israeli army spokesman told Reuters Israeli forces "managed to prevent an attack when they encountered a Palestinian man hurling a Molotov cocktail at them on the main road next to Silwad. They opened fire and they confirmed a hit."
In Washington, US State Department spokeswoman Jen Psaki called for a "speedy and transparent investigation."
"The United States expresses its deepest condolences to the family of a US citizen minor who was killed by the Israeli Defense Forces during clashes in Silwad on October 24," Psaki said.
She added that US officials would remain "closely engaged with the local authorities, who have the lead on this investigation."