Immune system ‘neutralized’ to accept incompatible kidney

For the first time in Israel, a man with one type of blood has donated his kidney to his daughter despite her incompatible blood type.

By JUDY SIEGEL
March 22, 2010 02:17
1 minute read.
Immune system ‘neutralized’ to accept incompatible kidney

kidney 88. (photo credit: )

 
X

Dear Reader,
As you can imagine, more people are reading The Jerusalem Post than ever before. Nevertheless, traditional business models are no longer sustainable and high-quality publications, like ours, are being forced to look for new ways to keep going. Unlike many other news organizations, we have not put up a paywall. We want to keep our journalism open and accessible and be able to keep providing you with news and analyses from the frontlines of Israel, the Middle East and the Jewish World.

As one of our loyal readers, we ask you to be our partner.

For $5 a month you will receive access to the following:

  • A user experience almost completely free of ads
  • Access to our Premium Section
  • Content from the award-winning Jerusalem Report and our monthly magazine to learn Hebrew - Ivrit
  • A brand new ePaper featuring the daily newspaper as it appears in print in Israel

Help us grow and continue telling Israel’s story to the world.

Thank you,

Ronit Hasin-Hochman, CEO, Jerusalem Post Group
Yaakov Katz, Editor-in-Chief

UPGRADE YOUR JPOST EXPERIENCE FOR 5$ PER MONTH Show me later

For the first time in Israel, a man with one type of blood has donated his kidney to another person – his daughter –  despite her incompatible blood type.

The successful operation, performed recently at the Rabin Medical Center-Beilinson Campus in Petah Tikva, was made possible by an unusual process in which the recipient’s immune system was neutralized to prevent it from fighting the donor organ.

Be the first to know - Join our Facebook page.


The 19-year-old girl, Ortal Mahlev, has suffered for years from renal insufficiency. The only way to save Ortal, who has type B blood, was to receive a kidney from someone with type B or Type O (the universal donor). Her father, who lives in Ramat Hasharon, has type A blood.

Because her condition had seriously deteriorated, the Rabin team decided to process her blood so that her immune system would not try to destroy her father’s kidney.

Prof. Eitan Mor and Dr. Alexander Yusis of the transplant department, along with Dr. Ya’acov Orlin of the blood bank, ordered a process of plasmapheresis to separate her antibodies from the rest of her blood and return the blood to her body to reduce the risk of rejection. Ortal also received drugs and blood products to help in this process.

As her father’s kidney is functioning normally in her body, Ortal was discharged on Sunday. Mor said that the technique, used in some leading centers abroad, is regarded as a breakthrough in organ transplantation, because it expands the supply of suitable organ donations and can succeed even for the long term with suitable monitoring of antibodies levels.

Join Jerusalem Post Premium Plus now for just $5 and upgrade your experience with an ads-free website and exclusive content. Click here>>

Related Content

[illustrative photo]
September 24, 2011
Diabetes may significantly increase risk of dementia

By UNIVERSITY OF MICHIGAN HEALTH SYSTEM