Marder out of woods, to leave ICU

27-year-old woman who suffered a rare case of near liver failure after taking ibuprofen for pain from a tooth extraction apparently will not need liver transplant.

By
April 4, 2011 05:32
1 minute read.
Shirli Marder

Marder 311. (photo credit: Courtesy)

 
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Shirli Marder, the 27-year-old woman who suffered a rare case of near liver failure after taking ibuprofen for pain from a tooth extraction, is “out of danger and apparently will not need a liver transplant,” the Rabin Medical Center- Beilinson Campus announced on Sunday.

Nearly two weeks after the shocking incident that won her and her family much public interest and sympathy, she still needs constant monitoring, but she was due to leave the intensive care unit on Sunday. Doctors said she has been attached to a plasmapheresis machine which performs, outside the body, the removal, treatment and return of components of blood plasma from blood circulation.

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This procedure is usually conducted for treating immunological disorders and, on the basis of her medical team’s judgment, came instead of a liver transplant.

Prof. Pierre Singer, head of Beilinson’s intensive care unit, said that Marder has improved significantly since she was rushed to Ben-Gurion Airport to fly to France for a transplant but was returned at the last minute to undergo a transplant – that was finally cancelled – here. But she still has a considerable way before her, he said.

Marder suffered the extreme reaction a few days after taking Nurafen, the commercial name of ibuprofen – one of the extremely common nonsteroidal antiinflammatory drugs (NSAIDS). Experts in the field of NSAIDS said that one should not take NSAIDS for no reason or in doses higher than those needed and listed on the packages.

But usually side effects are no worse than a skin rash.

The Marder case was one of fewer than half a dozen severe reactions recorded in the medical literature.



Ibuprofen has been manufactured and taken over the counter since the 1960s.

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