Police allowed traffic towards Tel Aviv on Highway 1 to resume after finding a bomb headed towards Jerusalem.
At least one suspect was pulled from his car and held in custody on the side of the road.
Traffic towards Jerusalem was still not allowed to move.
A helicopter flew overhead, and police cars, Shin Bet (Israel Security Agency) forces, and bomb squads were seen on site.
Police had told drivers to move away from their cars.
This comes after police went on high alert in Jerusalem, settting up roadblocks and detaining suspicious people.