A large blast in a warehouse near Bristol in England has caused multiple casualties, a spokeswoman for the fire brigade said on Thursday. The fire service had previously said on Twitter that it was responding to an incident after being called to a large explosion in Avonmouth, south west England. It said it had been joined there by the police and ambulance. 'We can confirm there are multiple casualties on site,' a spokeswoman for Avon Fire and Rescue Service said, adding that injuries were serious. 'The incident is ongoing,' the service said on Twitter.