In her first public response to the charges levied against her, Sara Netanyahu thanked the "thousands of supporters across the country and around the world who have given her encouragement and support" before boarding a plane to Argentina with her husband.
She and Prime Minister Benjamin Netanyahu will be visiting several countries in Latin America, marking the fifth time in some 15 months the prime minister will have embarked on a ground-breaking trip to countries never before visited by a sitting Israeli prime minister.
He will also visit the United States.
There will be good days and bad days, Sara Netanyahu said, and her supporters give her encouragement to do "all the real things that I do."
She didn't address the substance of the charges.
The prime minister, before boarding the plane for his ten-day trip, said he would be meeting with US President Donald Trump, and sent his regards to those suffering from Hurricane Irma.
"This storm too shall pass," he said.