Palestinians opened fire on Tuesday evening at an IDF outpost near Ramallah, on Route 443.
No casualties or damage were reported.
The shots apparently originated from the West Bank village of Ur al-Tahta and were not meant to hit vehicles on the road.
IDF troops were searching the area for the perpetrators.
Following the incident, National Union MK Michael Ben Ari said that the shooting was "the promo of what will happen if the High Court of Justice decision is implemented." Ben Ari was referring to a recent ruling that would see all checkpoints removed from the road, traversing the West Bank, and allow Palestinians to use the road freely.