"I hope to return with Naama, and I hope that this is the last trip to Moscow," said Yaffa before departing.
Naama was supposed to be transferred to a different prison in the past few days, but this did not happen.
"She is confused because they were supposed to transfer her to a different prison and they didn't transfer her," her mother said. "Maybe it's a good sign. We'll see what the attorney says after meeting with her."
Her 26-year-old daughter was sentenced to 7.5 years in a Russian prison for allegedly possession of 9.5 grams of cannabis.
The Kremlin said on Friday that the possible release of Naama Issachar was being held up because she had not yet formally requested to be pardoned.
In a meeting at Prime Minister Benjamin Netanyahu’s residence on Thursday, Russian President Vladimir Putin reassured Issachar’s mother, Yaffa, that “everything will be alright.”
The Kremlin’s spokesman, Dmitry Peskov, said it was impossible for Issachar to be granted a presidential pardon without her first formally requesting one.
Issachar’s attorneys are planning to discuss Peskov's statements with her.
Netanyahu has officially asked Putin for a humanitarian pardon for the woman, who was arrested in April at Moscow’s Sheremetyevo International Airport en route to Israel from India.
According to Yaffa, Putin told her “I will return your girl home,” but he did not say when. She described the Russian leader as charming and down to earth.