(photo credit: INGIMAGE)
A new test for sperm called MACS (magnetic-activated cell sorting) can raise the success rates of fertility treatments for couples whose cause for infertility is not known, according to Jerusalem’s Shaare Zedek Medical Center.
The technique was recently introduced in the hospital lab of Dr. Ephrat Schoenberger.
In at least a quarter of infertility cases, doctors have not been able to determine the cause. Fertility experts use advanced treatments to improve sperm quality and produce embryos for returning to the woman’s body via in-vitro fertilization.
Recent discoveries point to fragile DNA in the sperm cells as the cause of the failure to produce a pregnancy. At Shaare Zedek, the technology is used to carry out MACS and the sperm chosen are less fragile.
Prof. Hananel Holtzer, head of the hospital’s IVF unit, said that sperm with defective DNA often lead to a defective fetus and a high risk of miscarriage. To reduce the number of fragile sperm cells, they are “marked” with “microbeads” and put through a special sorting/filtration process so they are then allowed to impregnate the ova.
On a sabbatical at McGill University on Montreal, Holtzer learned and used the technique and recently published his work in the Journal of Assisted Reproduction and Genetics. “The research applied Halo Sperm technology for the first time, using the sperm of a man who survived cancer whose sperm were frozen before his chemotherapy treatment.
But his sperm were found to have very fragile DNA. By using this technique, his wife was able to get pregnant, and she gave birth to healthy twins.”
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People who increased their consumption of water by one, two or three cups daily decreased their total calorie intake from 68 to 205 calories daily and their sodium intake from 78 to 235 grams, according to a paper by University of Illinois kinesiology and community health Prof. Ruopeng An. They also consumed five to nearly 18 grams less sugar and decreased their cholesterol consumption from seven to 21 grams daily.
“The impact of plain water intake on diet was similar across race, ethnicity, education and income levels and body weight status,” An said.
“This finding indicates that it might be sufficient to design and deliver universal nutrition interventions and education campaigns that promote plain water consumption in replacement of beverages with calories in diverse population subgroups without profound concerns about message and strategy customization.” On average, participants consumed about 4.2 cups of plain water on a daily basis, accounting for slightly more than 30 percent of their total dietary water intake.
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His company, Bio- Min Technologies, is in the process of establishing licensing agreements with toothpaste and dental materials manufacturers around the world.
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