Artificial heart patients 311.
(photo credit: Eli Dadon )
A new international study suggests that stem cell transplantation can help treating Lupus in cases where traditional treatment fails to help.
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease, one of many autoimmune diseases in which the patient's immune system attacks his own body systems, causing inflammation and damage. It may involve many organs, such as the kidneys, joints, skin, and others.
Stem cell transplantation, a process in which stem cells from another
person are transferred to the patient, is meant to "reset" the
patient's immune system, thereby overcoming the innate defect.
This pilot clinical study, published in Annals of the Rheumatic
Diseases, included 15 patients with persistently active lupus
refractory to standard medical treatment. The patients underwent stem
cell transplantation. 13 of them were followed for over a year after
After transplantation, all patients showed clinical improvement,
measured by disease activity score and a set of clinical parameters.
After one year of follow-up, 11 patients continued having a decreased
disease activity while on minimal treatment.
These recent primary findings may lead the way to a new promising
treatment approach in patients with lupus, as well as in other
Source: Ann Rheum Dis 2010;69:1423-1429.To read more case studies and medical opinions about stem cells in the treatment of diseases go to