Study: Your friend's stem cell can cure Lupus

New study shows that stem cell transplantation is effective in treating lupus patients who respond poorly to standard treatment.

August 11, 2010 18:29
1 minute read.
Iluz (left) and Abuhatzeira, with Prof. Dan Aravot

Artificial heart patients 311. (photo credit: Eli Dadon )

A  new  international study suggests that stem cell transplantation can help treating Lupus in cases where traditional treatment fails to help.

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease, one of many autoimmune diseases in which the patient's immune system attacks his own body systems, causing inflammation and damage. It may involve many organs, such as the kidneys, joints, skin, and others.

Stem cell transplantation, a process in which stem cells from another person are transferred to the patient, is meant to "reset" the patient's immune system, thereby overcoming the innate defect.

This pilot clinical study, published in Annals of the Rheumatic Diseases, included 15 patients with persistently active lupus refractory to standard medical treatment. The patients underwent stem cell transplantation. 13 of them were followed for over a year after the treatment.

After transplantation, all patients showed clinical improvement, measured by disease activity score and a set of clinical parameters. After one year of follow-up, 11 patients continued having a decreased disease activity while on minimal treatment.

These recent primary findings may lead the way to a new promising treatment approach in patients with lupus, as well as in other autoimmune diseases.

Source:  Ann Rheum Dis 2010;69:1423-1429.

To read more case studies and medical opinions about stem cells in the treatment of diseases go to:

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