The third suffered only light injuries and was released from the hospital.
The IDF has decided to reinforce its West Bank combat forces, in light of the shooting, the IDF's spokesperson announced..
The three young men had been standing at a bus stop on Route 60, which is also a hitchhiking post. A gray car stopped, and a gunman fired at them from the vehicle.
A security video showed how people at the scene ducked for cover during the brief shooting.
“IDF troops are searching for the vehicle and are setting up roadblocks in the area,” the military said.
The three students were transported to Beilinson hospital in Petah Tikva. The Itamar Yeshiva where they studied asked the public to pray for their recovery.
Samaria Regional Council head Yossi Dagan, who went immediately to the scene, called the incident a terror attack.
Senior MDA medic Aviel Mamlia said that when he arrived at the scene, two of the injured were lying unconscious on the ground and one was sitting upright.
Medics treated the wounds and had to resuscitate one of the victims, he said.
“This is a serious incident,” Dagan said. To the Palestinians, he said, “You will never break us.”
A video of the scene showed a standoff between her and two soldiers. She advanced toward them, wearing a traditional black Palestinian dress and a black head covering, with a blue mask. A black bag was strapped over one shoulder and with the other hand, she appeared to hold a knife.
Two soldiers faced her with their guns drawn, wearing flak jackets and vests. They walked backward yelling at her to stop and put down the knife and she walked forward for a few moments, before they shot and critically injured her.
The Palestinian woman was evacuated to Shaare Zedek Medical Center in Jerusalem, where she later died of her wounds.
The attacks follow a renewed wave of Palestinian violence, linked partially to tensions arising from Israel’s refusal to publicly announce that Palestinians can vote in Jerusalem during their upcoming elections.
In the last few weeks, Hamas in Gaza has launched over 40 rockets at Israel, and violence between Jewish and Arab residents of Jerusalem rocked the city. That unrest has increasingly spread to the West Bank.
Prime Minister Benjamin Netanyahu and Defense Minister Benny Gantz condemned the attack.
“The security forces are in pursuit of the terrorists and I am certain that they will apprehend them as soon as possible,” Netanyahu said. “We will not allow terrorism to raise its head and we will strike our enemies with force.”
Several Palestinian groups, including Hamas, Islamic Jihad and PFLP, welcomed the ‘heroic’ shooting attack at Tapuah Junction: ‘The resistance will continue and the rifle is ready to defend Jerusalem and Al-Aqsa.’