Sirens sounded across southern Israel on Wednesday night after launches from Iran and Hezbollah.
Palestinians have reported several deaths in a village near Hebron due to the Iranian barrage.
Several falls were reported in the South by Israeli media, including in the towns of Neta and Beersheba.
Earlier Wednesday night, Israel received a barrage of rockets from Hezbollah in Lebanon in an attack that targeted northern, central, and southern Israel. It marked the first Hezbollah rocket attack on southern Israel since the beginning of Operation Roaring Lion.
Israeli media reported damage to a house in Kiryat Shmona following the barrage.
Earlier on Wednesday, three people were wounded in an Iranian ballistic missile attack on central Israel.
Magen David Adom teams were dispatched to a scene of impacted shrapnel in Kiryat Bialik and in Petah Tikvah.
MDA paramedics provided medical care to a 44-year-old man and his two children, aged 13 and 12, with mild head injuries.
"They [the injured] told us that while playing on the field, they were hit by shrapnel," Paramedic and director of the Petah Tikva MDA station Fadi Hamdan said.
Iranian missiles fall in central Israel, blow out walls of Ramat Gan apartment
A separate fall caused heavy damage to the ground-floor apartment of a building in Ramat Gan, according to Maariv. Two other apartments were damaged by the blast.
One apartment had a hole in its roof from the blast. At the other apartment, shrapnel was found strewn about, and the walls collapsed in, though an initial inspection indicates the damage did not affect the building's stability.
"We were in the shelter, and we heard, we knew it was ours. It was all dust and a loud boom, and the whole building shook; it was on us," Sara Ben Zion, one of the building's residents, told Maariv.
Planes at Ben-Gurion damaged in Iranian strikes
Separately, three private aircraft parked at Ben-Gurion Airport were struck by falls within the past few days, according to the Israel Airports Authority, causing severe damage but no casualties.
The Transportation Ministry is now considering reducing the number of passengers allowed per flight.
Two people killed, several wounded following overnight Iranian missile barrage
Yaron and Ilana Moshe, a couple in their 70s, were killed in Ramat Gan after being hit by shrapnel from Iranian missile interceptions early Wednesday morning, according to Magen David Adom.
Five others were lightly wounded during the attack, Israel Police stated. Eight other shrapnel impact sites were reported following the missile barrage.
Cars set ablaze in Holon after power line downed during overnight Iranian attack
Israel's Fire and Rescue Authority stated that a number of cars were set on fire after a power line was downed by an Iranian cluster munition in Holon.
Chief Fire Officer Oshri Bason said the fires occurred next to a residential building, but noted that there were no injuries.
Shrapnel falls on Tel Aviv train station
Israel Railways stated that shrapnel fell near the Tel Aviv Savidor Central train station, causing some damage to the station's platforms.
Trains to and from the station have been suspended, with shuttle services operating between Herzliya, Tel Aviv Savidor Central, and Ben-Gurion Airport.
An MDA vehicle operating in central Israel was also hit by shrapnel resulting from missile interceptions.
"A tough night for Ramat Gan," said Mayor Carmel Shama-Hacohen. "We are being hit with barrages, but this seems to be a deadly multi-launch barrage. I am at the central site, and it is a difficult scene. The picture is still unclear, the injuries are severe, and people have been hurt. We are deeply saddened and are focused on managing the situation at all the sites in the city. I urge the public to follow the instructions and protect your lives."
Home Front Command Chief Maj.-Gen. Shai Klepper called the impact in Ramat Gan a "very difficult site" during his visit to the area.
"Two civilians were killed in the incident, and I offer sincere condolences to their families," he said.
Klepper thanked Ramat Gan City Council and emergency services for their "quick and professional response," and clarified that Home Front Command forces continue to operate at every impact site, conducting searches and providing aid to civilians.