Italy's top court on Tuesday overturned the 2011 acquittal of American student Amanda Knox and her former boyfriend Raffaele Sollecito for the murder of Briton Meredith Kercher, and ordered a retrial.
The decision by the Court of Cassation is a new twist to a long-running case whose initial handling was sharply criticized by independent forensic experts.
Prosecutors accused Knox and Sollecito of killing Kercher in 2007 during a drug-fuelled sexual assault.
The two were initially found guilty and sentenced to 26 and 25 years in prison respectively after a trial that grabbed headlines all over the world.
In 2011, their convictions were overturned after forensic investigators challenged police scientific evidence, saying there had been multiple errors in the investigation. Knox and Sollecito were released after serving four years in prison.