Two trucks collided head-on at the Dimona junction in southern Israel on Monday afternoon.
One of the trucks, which had been transporting the toxic substance ammonia, caught fire following the collision.
Firefighters were successful in dousing the fire and managed to release the driver, who had been trapped in the truck.
His condition was not determined, and he was evacuated from the scene in an MDA ambulance.
However, the driver of the other truck remained trapped in his vehicle.
The harmful substances inside the truck did not leak and create an environmental hazard, Israel Radio reported.