Four people were killed in a highway car crash between near Ariel in the West Bank on Saturday night, Magen David Adom reported.
MDA and IDF paramedics provided initial treatment at the scene of the accident.
The victims were two men and two women in their 30s.
Four other people, ranging in age from 25 to 40, were seriously injured in the crash and were taken by ambulance and helicopter to Rabin Medical Center's Beilinson Campus in Petah Tikva.
An addtional person in unlisted condition was taken by Red Crescent paramedics to a hospital within the Palestinian Authority.