Missile fragments landed in central Israel's Ramat Gan following the launch of a cluster munition from Iran on Saturday afternoon.
Security forces and bomb sappers are en route to the sites of impact. One person in his 50s was lightly injured.
In Ramat Gan, multiple cars were destroyed by the missile fragments, and several apartments were impacted by the explosion. Magen David Adom said there is a possibility that people are trapped inside the affected sites.
The military also confirmed that the IDF's Home Front Command search and rescue forces were operating at the reported fall sites, and asked the public to stay away from areas damaged by missile shrapnel.
MDA: More than 10 fall sites reported
According to an MDA statement, more than 10 falls were reported in Tel Aviv, Bnei Brak, Petah Tikva, Givatayim, Ramat Gan, and Rosh HaAyin.
"We received reports of several crash scenes and went to the scene in ambulances, intensive care units, and MDA motorcycles. We arrived at the scene within a few minutes and saw destruction, fire, shattered glass on the floor, and a lot of smoke," said senior MDA medic Lior Paz.
"We began extensive scans of the scene, and fortunately, no casualties were found. We continue to scan the scenes and will remain here as long as necessary. Follow the instructions of the Home Front Command and enter a protected area during an alarm," he added.
Two more fragments landed in Bnei Brak, one of them against an apartment building, another fell on an empty road in Petah Tikva, and another one fell on an empty parking lot in Rosh HaAyin. No one was wounded in these incidents.