The grey cat with shining green, crossed eyes, has become a favorite with visitors, including former US President Barack Obama, who was filmed stroking her during a trip in 2009.
Hagia Sophia dates back to the sixth century and has a history as both a church and a mosque before it was turned into a museum.
Hagia Sophia is one of Turkey's most visited sites, attracting over 30 million visitors since 2007. It has been a museum since 1935.
The wounded were being treated at 18 nearby hospitals.
The plane broke apart as it touched down at Istanbul's Sabiha Gokcen airport on Wednesday evening.
Government officials have stated that the mayor was not detained.
“Jews!” she screamed in Turkish. The chorus responded: “Death!”
They watched as a small group of Turkish men broke their glass storefront, ripped up Arabic leaflets and signs and set them alight.
The initiative was undertaken by Turkish Airlines.