Concern over a possible radiation leak is growing as attempts to strike strategic sites in southern Israel raise the prospect of a medical and security nightmare. A direct hit on the reactor near Dimona could disperse radioactive particles that may penetrate body tissues, damage bone marrow, and rapidly impair some of the body’s most vital systems.

The fear surrounding a strike on the nuclear reactor near Dimona does not stem only from structural damage to the site, but mainly from the possibility that radioactive material could be released into the surrounding environment. In such a case, one of the main dangers would be ionizing radiation, which can penetrate the body and trigger destructive cellular damage.

At the molecular level, radiation can damage DNA in every cell in the body, either directly or indirectly by generating free radicals that cause severe oxidative stress. In cases of high-dose exposure, the body’s normal repair mechanisms may be overwhelmed. Cells stop dividing properly, and many begin apoptosis, a form of programmed cell death.

This destructive process unfolds along a broad timeline, with damage deepening as exposure worsens. In the first moments after significant radiation exposure, high-energy particles can break chemical bonds within cells. At that stage, severe injury may already have occurred even if the exposed person does not yet feel anything.

Within minutes to hours, depending on the radiation dose, symptoms may begin to appear. In very high-dose exposures, victims may suffer intense nausea, repeated vomiting, profound fatigue, and dizziness. These signs may indicate major damage to fast-dividing tissues and, in extreme cases, injury affecting the central nervous system. Loss of appetite and severe abdominal pain may also develop as cells lining the digestive tract begin to break down.

An infographic details how someone would react to direct radioactive contact.
An infographic details how someone would react to direct radioactive contact. (credit: VIA MAARIV ONLINE)

How would someone's body react to direct nuclear contact?

Within hours, the damage may become visible on the skin. Victims could develop redness, blistering, and radiation burns that resemble severe thermal burns but may penetrate deeper. At the same time, a quieter crisis may be developing in the bloodstream.

White blood cells, which defend the body against infection, can begin to die off in large numbers. Bone marrow, which produces new blood cells, may be so badly damaged that it cannot replace them. The result is a body left increasingly vulnerable to bacteria and viruses. As time passes, platelet counts may also fall, increasing the risk of uncontrolled internal bleeding.

In the following hours and days, the condition may deteriorate sharply with extreme exposure. Patients may suffer neurological symptoms, confusion, seizures, and loss of consciousness. At the same time, the gastrointestinal system may begin to collapse.

The cells lining the stomach and intestines die, open ulcerations can form, and bacteria may pass directly into the bloodstream. The result can include bloody diarrhea, severe dehydration, rapid weight loss, and overwhelming infections that the damaged immune system can no longer contain.

The geographic spread of radioactive material in the event of a strike on the reactor would depend heavily on wind conditions in the Negev. Prevailing northwesterly winds in the region could push a radioactive plume toward communities in the Arava and from there toward Jordan. A shift in wind direction, however, could redirect hazardous material toward Beersheba and nearby communities.

The healthcare system in southern Israel would face an unprecedented logistical challenge. Soroka Medical Center in Beersheba, the largest hospital in the region, could be forced to absorb thousands of casualties while also protecting its medical staff. Evacuating victims to hospitals in central Israel would be complicated by the need to move through potentially contaminated areas, which could require helicopters and protected intensive care ambulances.

One of the immediate tools used to reduce one specific long-term risk is potassium iodide, sometimes referred to in Israel as Lugol’s iodine. The thyroid gland tends to absorb radioactive iodine from the air, which can sharply raise the future risk of thyroid cancer.

Taking potassium iodide at the appropriate time can saturate the thyroid with stable iodine and reduce its absorption of radioactive iodine. These tablets do not protect the rest of the body from radiation damage. They protect the thyroid only.

There are also encouraging developments from the field of Israeli medical technology. Pluri, formerly Pluristem, has developed a placenta-based cell therapy, PLX-R18, for acute radiation syndrome. The treatment is designed to stimulate bone marrow recovery and support the production of new white blood cells, red blood cells, and platelets. The company says the therapy may be administered up to 96 hours after exposure and has shown promising survival benefits in preclinical studies.

Preparations for a scenario involving a strike on the Dimona reactor have long been part of Israel’s emergency planning. Although the threat is alarming, staying in a sealed, protected space can significantly reduce exposure to external radiation and help prevent the inhalation of hazardous particles. Medical knowledge accumulated over decades now allows physicians to understand far more clearly what happens inside the body after radiation exposure and to tailor treatment accordingly.

The combination of advanced Israeli medical technologies, civilian discipline, and preparedness among hospital teams would be central to coping with such an extreme event.

Remaining close to protected spaces and following Home Front Command instructions are not merely recommendations. They are critical steps that can save lives in a situation where every minute matters.