Best appetite suppressants OTC hunger control supplements

Can the best appetite suppressants help you lose weight? Find out our top picks and their ingredients, evidence behind them, and cost.

  (photo credit: PR)
(photo credit: PR)

Best Appetite Suppressants 2024: OTC Hunger Control Supplements for Weight Loss

Looking to naturally curb hunger and shed pounds? Discover appetite suppressants that make you feel full, eat less, and increase calorie burn. Want to suppress hunger for a meal, a day, or longer? Find practical advice here. 

This article unveils scientifically-supported appetite suppressants that are effective and use natural ingredients. We look at how they work, usage, and health benefits. 

See why PhenGold ranks highest and explore other options. Embrace a friendlier approach to weight loss with appetite suppressants—your allies in achieving your health goals.

Best Appetite Suppressants in 2024: First Look

1. PhenGold - Best Appetite Suppressant Overall

(Credit: PR)
(Credit: PR)

Pros

*Potent appetite suppressant and fat burner

*Contains natural ingredients

*Targets weight loss in multiple ways

*Good track record with over 190,000 satisfied customers

Cons

*May not be suitable for people sensitive to caffeine

Who Is PhenGold Best For?

PhenGold reviews show it is ideal for people aiming to kickstart their weight loss or overcome a weight loss plateau. Its multi-faceted approach to fat burning makes it suitable for individuals struggling with cravings or those looking for an extra metabolic boost.

Key Ingredients

*α-Lacys Reset

*Nopal

*Chromium picolinate

*Caffeine 

Summary

PhenGold is our favorite among the best appetite suppressants and fat burners. Its unique multi-action formula helps reduce appetite, boost metabolism, and increase energy levels. It's a reliable option for both men and women who want to lose weight.

>>Check the best prices for PhenGold

2. Trimtone - Best for Women

(Credit: PR)
(Credit: PR)

Pros

*Specifically designed for women

*Contains natural ingredients

*Single daily dose makes it easy to use

*60-day money-back guarantee

Cons

*Formula doesn’t disclose dosages

Who Is Trimtone Best For?

Trimtone is perfect for women who want something that focuses on enhancing metabolism and reducing appetite. If you’re a woman struggling with cravings or overeating, this product is ideal for you.

Key Ingredients

*Green tea

*Grains of paradise

*Caffeine

*Glucomannan

Summary

Trimtone is the best appetite suppressant formulated specifically for women. It helps burn calories faster, enhances fat metabolism, and suppresses appetite, making weight loss easier and more achievable for ladies.

>>Check the best prices for Trimtone

3. PhenQ - Best for Overcoming a Weight Loss Plateau

(Credit: PR)
(Credit: PR)

Pros

*Acts as both an appetite suppressant and fat burner

*Includes natural ingredients

*Targets weight loss in several ways

*60-day money-back guarantee

*Free shipping worldwide 

Cons

*May interact with antidepressants 

Who Is PhenQ Best For?

PhenQ is ideal for individuals planning to kickstart their weight loss or overcome a weight loss plateau. Its multi-pronged approach makes it suitable for people who want an all-in-one approach to weight loss in one bottle.

Key Ingredients

*α-Lacys Reset

*Capsicum extract

*Chromium picolinate

*Caffeine 

Summary

PhenQ is a holistic appetite suppressant and fat burner. Its unique multi-action formula helps reduce appetite, boost metabolism, and increase energy levels. It's a viable option for both men and women who are serious about losing weight.

>>Check the best prices for PhenQ

4. Phen24 - Best for Reducing Cravings

(Credit: PR)
(Credit: PR)

Pros

*Unique day and night formula

*Comprises natural ingredients

*Boosts metabolism and suppresses appetite

*Antioxidants may protect muscles

Cons

*Glucomannan may interact with medications

Who Is Phen24 Best For?

Phen24 is ideal for people searching for a 24/7 approach to weight loss. Its unique day-and-night formula makes it suitable for individuals who need a two-fold metabolic boost. It helps to reduce cravings round-the-clock.

Key Ingredients

*Caffeine 

*Guarana extract

*Hops

*Griffonia extract

Summary

Phen24 is a time-sensitive appetite suppressant and fat burner that works 24/7 to help you lose weight. Its day and night formula helps reduce appetite, boost metabolism, and promote better sleep, making weight loss easier and more achievable.

5. Zotrim - Best for Vegans

Pros

*Clinically proven appetite suppressant

*Contains natural ingredients

*Suitable for vegans

*Includes caffeine, vitamin B3, and vitamin B6 for energy 

Cons

*Can be slightly inconvenient to take each dose before meal

Who Is Zotrim Best For?

Zotrim is ideal for people looking for a scientifically supported appetite suppressant. Its natural ingredients make it suitable for individuals looking for a vegan-friendly weight loss solution.

Key Ingredients

*Yerba Mate leaf extract

*Guarana seed extract 

*Damiana leaf extract

Summary

Zotrim is an appetite suppressant supported by clinical trials that suggest it can help you eat less and reduce calories. It's a dependable option for both men and women wishing to lose weight.

6. Instant Knockout - Best for Athletes

Pros

*Developed for pro boxers and MMA fighters

*Comprises natural ingredients

*Targets stubborn fat

*Includes black pepper to enhance supplement absorption

*Same-day shipping available

Cons

*Glucomannan may interfere with medication absorption

Who Is Instant Knockout Best For?

Instant Knockout is ideal for athletes and fighters determined to maintain their physical condition during the cutting cycle. It's also a great option for individuals who want to control their hunger and need help losing weight rapidly with minimal health risks.

Key Ingredients

*Green tea extract

*Cayenne pepper seeds

*Glucomannan 

Summary

Instant Knockout is the best appetite suppressant and fat burner geared toward professional and amateur athletes. Its unique formula helps reduce appetite, boost metabolism, and increase energy levels. It can help both men and women lose weight while maintaining optimal physical performance.

7. Leanbean - Best Low-Stim Appetite Suppressant

Pros

*Contains a hefty dose of glucomannan

*Less stimulating than competing products

*Green coffee bean extract may enhance fat burning

Cons

*Glucomannan may reduce nutrient absorption

*Requires users to take six capsules daily

Who Is Leanbean Best For?

Leanbean is ideal for people who need a gentle boost of energy and a simple way to control their hunger. It contains a mix of herbal extracts that support your body’s natural fat-burning process and help you eat less. 

It’s also lightly stimulating, with the energy coming from green coffee beans, which are slower to release than caffeine anhydrous. This makes it suitable for both women and men sensitive to stimulants or have trouble with cravings.

Key Ingredients

*Green tea

*Grains of paradise

*Glucomannan

*Green coffee beans

Summary

Leanbean is the best appetite suppressant for people who prefer supplements with minimal caffeine content. It uses a high dose of glucomannan to help you feel satisfied for longer, making it easier to lower your calorie intake without feeling jittery.

What Are Appetite Suppressants?

Appetite suppressants are supplements that claim to help reduce hunger and food intake by influencing the body’s natural processes or appetite hormones. These products are usually derived from herbs, plants, or other natural sources with some scientific evidence of affecting appetite in humans or animals. 

Benefits of Using the Best Appetite Suppressants

Natural appetite suppressants may provide several advantages for weight loss and overall health. Here are some benefits of using appetite suppressants:

Generally Safe With a Low Risk of Side Effects

Natural appetite suppressants are comparatively safer than some prescription appetite suppressants, which may have serious side effects such as increased blood pressure, heart palpitations, insomnia, and dependence. In contrast, these supplements are generally safe and well-tolerated by most people. 

Natural appetite suppressants do not typically contain synthetic chemicals or stimulants that may interfere with the body’s natural processes. 

Help Improve Blood Sugar and Cholesterol Levels 

Some natural appetite suppressants can help regulate blood sugar and cholesterol levels. For instance, glucomannan, a soluble fiber that can absorb water and form a gel in the stomach, can slow down the digestion and absorption of carbohydrates and fats. It may lower blood sugar and cholesterol levels after meals. 

Increase Feelings of Fullness

One of the main ways that natural appetite suppressants work is to increase feelings of fullness and satisfaction after eating. This can help reduce the amount of food you eat and prevent overeating or binge eating. 

Reduce Cravings and Emotional Eating

Another benefit of natural appetite suppressants is that they can help reduce cravings and emotional eating, which are often triggered by stress, boredom, or negative emotions. 

Some natural appetite suppressants can manage the activity of neurotransmitters such as serotonin and dopamine, which are involved in mood regulation and reward processing. 

>>Check the best prices for PhenGold

How To Choose The Best Appetite Suppressants

When choosing the best appetite suppressants, consider the following factors:

Company Reputation 

Check online reviews, ratings, testimonials, and feedback from other customers to get an idea of how trustworthy and reliable the company is. Moreover, look for any certifications, accreditations, or awards that the company has received from credible organizations.

High-Quality Ingredients

You should avoid products that contain artificial additives, fillers, preservatives, or synthetic substances that may cause adverse effects or interfere with the absorption or effectiveness of the active ingredients. 

Make sure to check the label for the dosage, potency, and purity of each ingredient. Confirm that the components are backed by scientific research and clinical trials.

Side Effects and Safety

Find products with a low risk of side effects and are generally safe for long-term use. 

Consult your doctor before taking any supplements, especially if you have any medical conditions and allergies or are taking any medications. 

Follow the directions and precautions on the label, and do not exceed the recommended dosage. 

Affordability

Consider products that are reasonably priced and offer good value for money. Compare the cost per serving, the number of servings per bottle, and the quality and quantity of ingredients among different products and brands. 

Research the available discounts, coupons, promotions, or free shipping offers that the company may provide to save money and get the best deals.

>>Check the best prices for PhenGold

Product Effectiveness

Search for the best weight loss supplements that potentially deliver fast and lasting results and help you achieve your weight loss goals. Look for evidence of product effectiveness from customer reviews, testimonials, before-and-after photos, and success stories. 

Furthermore, check if the products have a money-back guarantee or a free trial offer that allows you to try the product risk-free and see if it works for you.

Refund Policies

Check how long you have to return the product, what condition it has to be in, what proof of purchase you need to provide, and how you will receive your refund. Finally, confirm if there are any shipping costs, handling fees, or restocking fees that may apply.

Common Ingredients

Some popular ingredients usually included in natural OTC appetite suppressants are:

Conjugated Linoleic Acid

This type of fat is found in dairy products, beef, and lamb. It may help reduce body fat, increase lean muscle mass, and improve metabolic health [1].

Fenugreek

This herb with high amounts of soluble fiber can slow down digestion and make you feel more satisfied. It may also help regulate blood sugar and cholesterol levels [2].

Garcinia Cambogia

This tropical fruit contains hydroxycitric acid (HCA), which may inhibit an enzyme that produces fat in the body [3]. It may also increase serotonin levels, which could reduce appetite and improve mood.

Glucomannan

This type of fiber comes from the root of the konjac plant. It can absorb water and form a gel-like substance in the stomach, which can make you feel full and delay stomach emptying [4]. It may also lower blood sugar, cholesterol, and triglycerides.

Caralluma Fimbriata

This cactus-like plant has been used as a famine food in India for centuries. It may suppress hunger by affecting the brain’s appetite center and increasing the feeling of fullness [5].

>>Check the best prices for PhenGold

Green Coffee Bean Extract

This extract comes from unroasted coffee beans, which contain chlorogenic acid and caffeine. Chlorogenic acid may slow down the absorption of carbohydrates and fat in the gut, while caffeine may boost metabolism and energy expenditure [6].

Green Tea Extract

This extract is made from the leaves of the Camellia sinensis plant, which include catechins and caffeine. Catechins are antioxidants that may increase fat burning and thermogenesis, while caffeine may stimulate the nervous system and reduce appetite [7].

Chromium Picolinate

This mineral is involved in the metabolism of carbohydrates, fats, and proteins. It may enhance the action of insulin, a hormone that regulates blood sugar and hunger signals [8].

Cayenne Pepper

This spice contains capsaicin, a compound that gives peppers their heat. Capsaicin may increase the production of heat in the body, which can burn more calories and suppress appetite [9].

>>Check the best prices for PhenGold

Prescription Appetite Suppressants

Some of the most common prescription appetite suppressants are:

*Phentermine: It is one of the oldest and most widely used appetite suppressants. This medication stimulates the release of norepinephrine, a hormone that increases alertness and energy. It also reduces the activity of neuropeptide Y, a brain chemical that triggers hunger.

*Phendimetrazine: It is similar to phentermine but has a shorter duration of action. This medicine also increases norepinephrine levels and decreases neuropeptide Y levels in the brain.

*Diethylpropion: It is another medication that boosts norepinephrine and suppresses neuropeptide Y. It may also increase serotonin, a neurotransmitter that regulates mood and appetite.

*Liraglutide: This medication has similar effects as glucagon-like peptide-1 (GLP-1), a hormone released from the gut after eating. GLP-1 stimulates insulin secretion, lowers blood sugar, and slows down gastric emptying. It also reduces appetite by activating receptors in the brain that signal fullness.

What Are the Risks of Using the Best Appetite Suppressants?

Here are some risks of using natural appetite suppressants:

*Some appetite suppressants may cause gastrointestinal discomfort, such as gas, bloating, diarrhea, and constipation. 

*Certain natural appetite suppressants may increase blood pressure, which can be dangerous for people with cardiovascular problems or who are taking blood pressure medications. 

*Some appetite suppressants may have adverse drug interactions. This is especially true for those that contain hydroxycitric acid (HCA), such as garcinia cambogia and green coffee bean extract. They can interact with some antidepressants and antidiabetic medications, so they should be avoided by people taking these medicines.

>>Check the best prices for PhenGold

Frequently Asked Questions

Here, we answer a few frequently asked questions about the best appetite suppressants.

How Much Do the Best Appetite Suppressants Cost?

The cost of the best appetite suppressants varies depending on the type, brand, dosage, and duration of use. Prescription appetite suppressants are usually covered by insurance, but they may have copays or deductibles. 

Over-the-counter appetite suppressants are not covered by insurance and may range from $10 to $100 per month. Natural appetite suppressant supplements may also vary in price depending on the quality, quantity, and ingredients. 

It is crucial to compare different products and read customer reviews before buying any appetite suppressants.

How Long Should You Take Appetite Suppressants?

The duration of use of appetite suppressants depends on the type, effectiveness, safety, and personal preference of the user. Some prescription appetite suppressants are only approved for short-term use of 12 weeks or less, while others can be used indefinitely with a doctor’s approval. 

>>Check the best prices for PhenGold

Who Should Not Take Appetite Suppressants?

People who should not take appetite suppressants include those with allergies to any of the ingredients, heart disease, high blood pressure, diabetes, kidney or liver problems, glaucoma, thyroid disorders, bipolar disorder, seizures, eating disorders, or a history of drug and alcohol abuse. Pregnant or breastfeeding women should avoid taking appetite suppressants as well.

It is essential to check with a healthcare provider before taking any appetite suppressants.

Does Insurance Cover Appetite Suppressants?

Generally, prescription appetite suppressants are more likely to be covered by insurance than over-the-counter or natural supplements. 

However, some insurance companies may require prior authorization, proof of medical necessity, or evidence of weight loss before covering the cost of the medication. It is advisable to contact the insurance company and the healthcare provider before starting any appetite suppressant treatment.

When Is the Best Time To Take Hunger Suppressants?

The best time to take hunger suppressants depends on the type of product and your personal preference. Some products may work better when taken before meals, while others may work better when taken between meals or at night. 

Some products may also have specific instructions for when to take them based on their ingredients or effects. It is advisable to follow the directions on the label or consult a healthcare provider before taking any hunger suppressant.

Are Appetite Suppressant Pills Safe for Weight Loss?

Natural appetite suppressant pills can be generally safe for weight loss if they are used correctly. Since they are made from natural ingredients, the risk of side effects is slow.

However, they may have some minor side effects that usually subside with use. Some common side effects of appetite suppressant pills include nausea, vomiting, constipation, diarrhea, dry mouth, and headaches.

Monitor any changes in your health or well-being while taking appetite suppressant pills. If the symptoms persist, consult your doctor and stop taking the supplement.

>>Check the best prices for PhenGold

How Much Weight Can You Lose With Appetite Pills?

On average, people who combine natural appetite suppressants with healthy lifestyle changes, such as a nutritious diet and exercise, lose 3% to 9% of their starting weight over the course of a year. 

However, some people may lose more or less weight depending on their individual response to the supplement. Set realistic and healthy weight loss goals and use the supplement together with a balanced diet and regular workout routine.

Final Thoughts on the Best Appetite Suppressants

We have carefully examined the market and selected the seven best appetite suppressants for hunger control. PhenGold is our top pick, but the other six supplements also passed our high standards.

While appetite suppressants can be a valuable tool in your weight loss journey, remember that these supplements are most effective when combined with a healthy diet and regular exercise. 

Always consult with a healthcare professional before starting any new supplement regimen, particularly if you have a medical condition or are taking other medications.

References:

  1. Lehnen, Tatiana Ederich, et al. “A Review on Effects of Conjugated Linoleic Fatty Acid (CLA) upon Body Composition and Energetic Metabolism.” Journal of the International Society of Sports Nutrition, 17 Sept. 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4574006/.
  2. Gaddam A, Galla C, Thummisetti S, Marikanty RK, Palanisamy UD, Rao PV. Role of Fenugreek in the prevention of type 2 diabetes mellitus in prediabetes. J Diabetes Metab Disord. 2015 Oct 2;14:74. doi: 10.1186/s40200-015-0208-4. PMID: 26436069; PMCID: PMC4591578.
  3. Ji-Eun Kim et al. “Does Glycine Max Leaves or Garcinia Cambogia Promote Weight-Loss or Lower Plasma Cholesterol in Overweight Individuals: A Randomized Control Trial.” Nutrition Journal, U.S. National Library of Medicine, https://pubmed.ncbi.nlm.nih.gov/21936892/
  4. Kaats, Gilbert R et al. “Konjac Glucomannan Dietary Supplementation Causes Significant Fat Loss in Compliant Overweight Adults.” Journal of the American College of Nutrition, 1-7. 22 Oct. 2015, doi:10.1080/07315724.2015.1009194 
  5. Griggs JL, Su XQ, Mathai ML. Caralluma Fimbriata Supplementation Improves the Appetite Behavior of Children and Adolescents with Prader-Willi Syndrome. N Am J Med Sci. 2015 Nov;7(11):509-16. doi: 10.4103/1947-2714.170611. PMID: 26713299; PMCID: PMC4683806.
  6. Haidari, Fatemeh et al. “Energy restriction combined with green coffee bean extract affects serum adipocytokines and the body composition in obese women.” Asia Pacific journal of clinical nutrition vol. 26,6 (2017): 1048-1054. doi:10.6133/apjcn.022017.03
  7. Hodgson B. Adrian et al. “The Effect of Green Tea Extract on Fat Oxidation at Rest and during Exercise: Evidence of Efficacy and Proposed Mechanisms.” Advances in Nutrition (Bethesda, Md.), American Society for Nutrition, 1 Mar. 2013, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649093/
  8. Havel PJ. A scientific review: the role of chromium in insulin resistance. Diabetes Educ. 2004;Suppl:2-14. PMID: 15208835.
  9. Thornton, Tammy et al. "Capsaicin: A Potential Treatment to Improve Cerebrovascular Function and Cognition in Obesity and Ageing." Nutrients vol. 15,6 1537. 22 Mar. 2023, doi: 10.3390/nu15061537

Author Details

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Jamila Khan

Jamila@paradisemedia.com 

Jamila Khan is a practicing doctor of dental medicine with a passion for creating content in several niches, particularly the health and wellness space. She specializes in consumer health, mental health, sleep health, health technology, and women’s health.

Fact Checker Details

Fact Checker

Fact Checker Email

Daniel Boyer M.D

boyermd@farrinstitute.org 

Daniel Boyer is a practicing Doctor of medicine with a passion for medical research. He specializes in molecular biology, histology, and pharmacology.

This is a sponsored article. The article should not be considered as advice.

This is a sponsored article. The article should not be considered as advice.