An incoming Iranian attack on central Israel cut short a live televised briefing by Israel's military spokesperson Brig.-Gen. Effie Defrin on Friday evening, an Israeli official said.
The IDF had attacked the nuclear facility in Isfahan, the largest uranium enrichment facility in Iran, Defrin announced on Friday.
The IDF also announced that it had hit over 200 targets in Iran.
Iranian air defenses were activated on Friday evening in central Tehran, where Ayatollah Ali Khamenei's compound and the presidential office are located, Iranian state media reported.
Israel plans to target Iranian government leaders in Tehran if Iran launches missiles toward Israeli population centers, N12 reported on Friday evening, citing a senior security source.
US issues security alerts for Iran, Iraq, Israel and Jordan, warns of missile attacks
The US State Department issued security alerts on Friday for several Middle Eastern countries, in some cases advising against travel and warning of possible missile attacks after Israel launched military strikes against Iran.
It warned American citizens not to travel to Iran and said those there should leave. "US citizens who are unable to depart Iran should shelter in place," the advisory read.
The alerts warned of missiles, drones or rockets flying over Iraqi and Jordanian airspace. "In the event of such an incident seek overhead cover and shelter in place. Do not expose yourself to falling debris," the department said.