The attack was carried out between the villages of Al-Assad and Al-Dimas.
Russia fired 43 cruise missiles at targets overnight. Ukrainian air defenses shot down 36 of them.
This is the fifth attack attributed to Israel in two months in Syrian territory.
Kharkiv's schools have been forced to teach online throughout the war as some Russian missiles can reach the city in under a minute - not enough time to get from many classrooms to a shelter.
Russian military aircraft were damaged and civilian aviation was disrupted in the drone attacks, said Russian officials.
The bodies of two people were found in a nonresidential building and one person was wounded by glass shards, following a Russian missile attack on Kyiv.
Missile debris also damaged the roof of a house and fell on a complex of country homes in the capital's northern Obolon district.
North Korea launched two ballistic missiles eastward early on Wednesday, the Japanese Defense Ministry said.
Russian missiles once again pound the Ukrainian city of Kramatorsk. Three children are among the nine confirmed killed when one such missile hit a restaurant on Tuesday.
Russia strikes Kremenchuk, Ukraine exactly one year after a strike on the same location killed over a dozen people.
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