This was the first scrambling of the Dutch fighters since deployed at the Malbork air base in northern Poland.
Ukraine has in the past made public diplomacy pushes on the supply of Western warplanes to its air force, often focusing on American-made F-16 Falcons.
The "Juniper Oaks" drills are meant to demonstrate and deepen integration between the US and Israeli militaries.
The sale of F-16s is now becoming another way that Ankara is making demands for more weapons and seeking to trade this sale for dropping its opposition to letting Finland and Sweden join NATO.
Foreign Minister Mevlut Cavusoglu will discuss the sale of F-16 fighter jets along with NATO membership.
This move by the US stems from an increasingly expanding focus on information security and safeguarding US interests.
Israel's F-35 fighter jets and six F-15s from the US Air Forces Central Command took part in multi-day joint drills in souther Israel on Wednesday.